Recombinant Human IL-5 Protein, His-Fc tag-细胞生物学检测-试剂-生物在线
翌圣生物科技(上海)股份有限公司
Recombinant Human IL-5 Protein, His-Fc tag

Recombinant Human IL-5 Protein, His-Fc tag

商家询价

产品名称: Recombinant Human IL-5 Protein, His-Fc tag

英文名称: Recombinant Human IL-5 Protein, His-Fc tag

产品编号: 90195ES10

产品价格: 0

产品产地: Yeasen

品牌商标: Yeasen

更新时间: 2024-12-10T13:18:22

使用范围: null

翌圣生物科技(上海)股份有限公司
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 产品简介

 

Interleukin 5 (IL-5) is a member of the hematopoietic Th2 cytokine family and consists of 115 amino acids. Unlike other members of the cytokine family (IL-3 and GM-CSF), this glycoprotein is activated as a homologous dimer. IL-5 is secreted by Th2 cells and mast cells. Its biological activity on B cells and other cell types suggests that IL-5 is functionally important for Th2 cell activity. By binding to its receptor, IL-5 stimulates B cell growth and enhances immunoglobulin secretion. It is also a key factor in the activation of eosinophils. IL-5 has been associated with a variety of diseases, including allergic rhinitis and asthma, with substantial increases seen in circulating tissue, tracheal tissue, and a decrease in sputum eosinophils.

 

性能参数

 

Synonyms

TRF,Interleukin-5

Uniprot No.

P05113-1

Source

Recombinant Human IL-5 Protein is expressed from HEK293 Cells with His tag at the N-terminal and Fc tag at the C-terminal. It contains Ile20-Ser134.

Molecular Weight

The protein has a predicted MW of  45.33 kDa.

Purity

> 95% as determined by SDS-PAGE.

Endotoxin

<0.1 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).

Reconstitution

Centrifuge tubes before opening. The concentration of protein solution used for lyophilization is generally 1mg/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 ug/mL.

 

储存条件

 

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