FITC标记的谷氨酸受体红藻氨酸离子1抗体
产品名称： FITC标记的谷氨酸受体红藻氨酸离子1抗体
英文名称： Anti-GRIK1/FITC
产品编号： HZ-12031R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-GRIK1/FITC Conjugated antibody
FITC标记的谷氨酸受体红藻氨酸离子1抗体
| 英文名称 | Anti-GRASP/FITC |
| 中文名称 | FITC标记的一般受体磷酸肌醇相关支架蛋白1抗体 |
| 别 名 | General Receptor for phosphoinositides 1; GRASP1; General receptor for phosphoinositides 1-associated scaffold protein; GRASP; GRASP_HUMAN; GRP1 (general receptor for phosphoinositides 1) associated scaffold protein; GRP1 associated scaffold protein; GRP1-associated scaffold protein; Tamalin. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 神经生物学 细胞膜受体 细胞骨架 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 45kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GRASP/General Receptor for phosphoinositides 1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 metabotropic glutamate receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C-terminal PDZ-binding motif. Alternately spliced transcript variants have been observed for this gene.[provided by RefSeq, Dec 2012] Function: Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. Subunit: Heteromer. Composed of GRASP, PSCD2 and at least one GRM1. Also interacts with PSCD3, GRM2, GRM3 and GRM5 Subcellular Location: Cytoplasm, perinuclear region (By similarity). Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Cell junction, synapse, postsynaptic cell membrane (By similarity). Note=Localized at postsynaptic membranes. Similarity: Contains 1 PDZ (DHR) domain. Database links: Entrez Gene: 160622 Human Entrez Gene: 56149 Mouse Entrez Gene: 192254 Rat Omim: 612027 Human SwissProt: Q7Z6J2 Human SwissProt: Q9JJA9 Mouse SwissProt: Q8R4T5 Rat Unigene: 407202 Human Unigene: 621295 Human Unigene: 276573 Mouse Unigene: 82758 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
谷氨酸受体是哺乳动物大脑中主要的兴奋性神经递质受体，在各种正常的神经生理过程中被激活。该基因产物属于谷氨酸受体的海人酸盐家族，由四个亚基组成，具有配体激活离子通道的功能。该基因编码的亚基在第二跨膜结构域内受到RNA编辑（CAG->CGG；Q->R），被认为改变了离子流的性质。选择性剪接，导致转录变体编码不同的异构体，已经注意到这个基因。[ RefSeq，JUL 2008 ]