HLA-DR抗体-抗体-抗体-生物在线
北京索莱宝科技有限公司
HLA-DR抗体

HLA-DR抗体

商家询价

产品名称: HLA-DR抗体

英文名称: HLA-DR/HLA DRB1

产品编号: bs-1198R

产品价格: null

产品产地: 北京

品牌商标: BIOSS

更新时间: 2025-01-24T10:30:11

使用范围: WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,

北京索莱宝科技有限公司
  • 联系人 : 索莱宝-龚思雨
  • 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
  • 邮编 : 101102
  • 所在区域 : 北京
  • 电话 : 178****1073 点击查看
  • 传真 : 点击查看
  • 邮箱 : 3193328036@qq.com
  • 二维码 : 点击查看

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq]