Anti-GRN Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002553P-50ul	solarbio	50ul	960.00元
K002553P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-GRN Polyclonal Antibody
别名	CLN11;GEP;GP88;PCDGF;PEPI;PGRN
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human
蛋白分子量	64kDa
Gene ID	2896
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human GRN
性状	液体
Public Immunogen Range	Recombinant protein of human GRN
Subcellular Locations	Secreted
Swiss Prot	P28799
克隆类型	Polyclonal Antibody
背景资料	Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.